Oscar Yanes received his Ph.D. degree in Biochemistry (2006) from the Universitat Autonoma de Barcelona. In 2007 he became Research Associate in Gary Siuzdak’s lab at The Scripps Research Institute. Since 2011 Dr. Yanes coordinates the Metabolomics Platform of the CIBERDEM-URV, he is affiliated member at the IRB Barcelona and Assistant Professor at the URV where he also leads his own research group (www.yaneslab.com).
The two major aspects of Dr. Yanes research are: (i) the development of new methodology and computational tools in mass spectrometry (MS) and NMR-based metabolomics; and (ii) the study of fundamental biological processes (e.g., health and disease) using metabolomics in combination with other omic platforms.
Such efforts have led to the development of new methodology in mass spectrometry (Nature, 2007; Nature Protocols, 2008; Analytical Chemistry, 2009; Analytical Chemistry, 2010), and novel strategies for compound spectra extraction, peak annotation and de novo identification and characterization of known and unknown metabolites by LC-MS (Analytical Chemistry, 2015; Analytical Chemistry, 2017), GC-MS (Analytical Chemistry, 2016) and NMR (Angewandte Chemie Int Ed. 2017) for global metabolite profiling.
Dr. Yanes is involved in multi-disciplinary studies combining metabolomics with other omic approaches including proteomics, epigenomics and metagenomics, and novel molecular biology techniques to interrogate relevant areas such as stem cell biology (Nature Chemical Biology, 2010; Cell Research, 2011; Nature Cell Biology, 2018), diabetes (Scientific Reports, 2016; Molecular Metabolism, 2016; International Journal of Obesity, 2018), neuropathic pain (Nature Chemical Biology, 2012), cancer (Scientific Reports, 2017; Nature Communications, 2016) and other fundamental biological processes in disease (Science, 2016; Nature Communications, 2016; Nature Structural and Molecular Biology, 2017) involving animal models and human samples.