Reversing a dystopian future. New strategies to discover antibacterial agents

#BDAntimicrobialResistance

Reversing a dystopian future. New strategies to discover antibacterial agents

November 12, 13 and 14, 2019

CosmoCaixa Barcelona. c/Isaac Newton, 26. Barcelona

https://en.xing-events.com/BD_Antimicrobial_Resistance.html

Scientific leaders

Jordi Vila
Barcelona Institute for Global Health (ISGlobal)
Sara M. Soto
Barcelona Institute for Global Health (ISGlobal)
Clara Ballesté-Delpierre
Barcelona Institute for Global Health (ISGlobal)

Poster

aff_bd_antimicrobians_a0_v2_compressed.pdf

Program

bd19_amr_programa_web.pdf

Send your abstract

https://en.xing-events.com/BD_Antimicrobial_Resistance.html

Tabs

Description

Bacterial resistance to antimicrobial drugs is a serious problem in many aspects: it threatens our ability to treat infectious diseases, increases health costs, and poses a serious risk to the progress made in global health by individuals and communities in the past decades. Infections caused by multidrug-resistant bacteria are globally recognized as an emergent disease and antimicrobial resistance is a priority for global health action as declared by institutions such as the World Health Organization and the European Centre for Diseases Control.

When resistance to first-line drugs increases, infections last longer and become more expensive to treat, with hospitalization required in many cases. To fight antimicrobial resistance we need to promote innovation, research and the development of new tools.

This B·Debate, a joint initiative of Biocat and “la Caixa” Foundation, is co-organized with the Barcelona Institute for Global Health (ISGlobal) in order to:

Offer an overview of the current research strategies that are being developed
Identify the success and limitations of the different research lines
Discuss how the future in antimicrobial drug discovery looks like
Identify the interventions that are currently taken and should be carried out in terms of policies to stimulate research in this field and implement measures to tackle antimicrobial resistance.

Confirmed speakers:

• Alex Soriano, Hospital Clínic, Barcelona
• Brice Felden, Bacterial regulatory RNAs & Medicine, France
• Domingo Gargallo-Viola, ABAC Therapeutics, Barcelona
• Eduard Torrents, IBEC, Barcelona
• Els Beirnaert, Aelin Therapeutics, Belgium
• Francesc Rabanal, Facultat de Química (UB), Barcelona
• Gaetano Castaldo, Research Executive Agency, EC, Belgium
• Gemma Buckland Merrett, Wellcome Trust, UK
• Hasan Jafri, AstraZeneca, USA
• Javier Garau, Clínica Rotger Quirónsalud, Spain
• Jean-Denis Docquier, University of Siena (Dpt of Medical Biotechnology), Italy
• Jesús Rodriguez-Baño, Hospital Universitario Virgen Macarena, Spain
• Joan Gavaldà, VHIR, Barcelona
• Joan Bigorra, ISGlobal, Barcelona
• Jordi Vila, ISGlobal, Barcelona
• Laura Marin, JPI-AMR, Sweden
• Laurence Roope, Health Economics Research Centre (HERC), UK
• Luis Martínez-Martínez, Hosp. Univ. Reina Sofía (Córdoba). Junta de Andalucia, Spain
• Olga Genilloud, Fundación Medina (IIMENA), Spain
• Patrick Jault, Freelance, France
• Sara Soto, ISGlobal, Barcelona
• Seamus O'Brien, GARDP, Switzerland
• Ursula Theuretzbacher, Center of Anti-Infective Agents, Austria
• Younes Smani, Institute of Biomedicine of Seville, Spain

Registration is already OPEN! Early bird price available until September 30

Submit your abstract for a flash talk presentation until October 15

Agenda

Tuesday, November 12,2019
14:45	Registration & welcome coffee
15:15	Welcome
	DAY 1: STATE-OF-THE-ART OF ANTIMICROBIAL RESISTANCE SESSION 1
15:30	Overview of the current situation of antimicrobial resistance Jordi Vila (Barcelona Institute for Global Health (ISGlobal), Barcelona)
15:50	The economic challenges of antimicrobial resistance Laurence Roope (Health Economics Research Centre (HERC), Oxford, UK)
16:10	Current pipeline of new antibiotics Ursula Theuretzbacher (Centre of Anti-Infective Agents, Vienna, Austria)
16:30	Coffee break and networking
	SESSION 2
17:00	Old drugs revisited Jesús Rodríguez-Baño (Hospital Universitario Virgen Macarena, Seville, Spain)
17:20	Antibiotic combination therapy Javier Garau (Clínica Rotger Quirónsalud, Palma de Mallorca, Spain)
17:40	Do we really need new antimicrobials? Luis Martínez-Martínez (University Hospital Reina Sofía and University of Cordoba, Córdoba, Spain)
18:00	Networking cocktail

Wednesday, November 13, 2019
9:00	Registration & welcome coffee
	DAY 2: NEW APPROACHES FOR THE DISCOVERY OF NEW ANTIMICROBIAL AGENTS SESSION 3
9:20	Secondary metabolites with antibacterial activity Olga Genilloud (Fundación Medina (IIMENA), Granada, Spain)
9:40	Oceans as natural source of antibiotics Sara M. Soto (Barcelona Institute for Global Health (ISGlobal), Barcelona)
10:00	Design of synthetic antibiotics Domingo Gargallo-Viola (ABAC Therapeutics, Barcelona)
10:20	Coffee break and networking
	SESSION 4
10:50	Microbiota as a therapeutic approach Àlex Soriano (Hospital Clínic, Barcelona)
11:10	*Novel mAbs Against Serious Pseudomonas aeruginosa* Infections: Are We Ready for a Paradigm Change?** Hasan Jafri (AstraZeneca, Gaithersburg, USA)
11:30	New drug delivery systems to treat bacterial infections Eduard Torrents (IBEC, Barcelona)
11:50	*Efficacy and tolerability of a cocktail of bacteriophages against Pseudomonas aeruginosa* to treat infected burn wounds** Patrick Jault (Paris, France)
12:10	Nano technology for AMR infections Joan Gavaldà (VHIR, Barcelona)
12:30	Lunch
	SESSION 5
13:30	Antimicrobial cyclic peptides: the case of polymyxins Francesc Rabanal (University of Barcelona, Barcelona)
13:50	Harnessing the power of protein aggregation to develop new antibiotics Els Beirnaert (Aelin Therapeutics, Leuven, Belgium)
14:10	Reversing β -lactam resistance with new β -lactamase inhibitors Jean-Denis Docquier (University of Siena, Siena, Italy)
14:30	Antivirulence drugs Younes Smani (Institute of Biomedicine of Seville, Seville, Spain)
14:50	Coffee break and networking
15:10	Novel antibiotics effective against gram-positive and -negative multi-resistant bacteria with limited resistance Brice Felden (Rennes University, Rennes, France)
15:30	Discussion panel: Open discussion on new research strategies Moderated by Javier Vega (EIT Health Spain, Barcelona) Brice Felden (Rennes University, Rennes, France) Domingo Gargallo-Viola (ABAC Therapeutics, Barcelona) Eduard Torrents (IBEC, Barcelona) Olga Genilloud (Fundación Medina (IIMENA), Granada, Spain)
16:00	Closing remarks and farewell

Thursday, November 14, 2019
9:00	Registration & welcome coffee
	DAY 3: BEYOND THE DISCOVERY OF NEW ANTIMICROBIAL AGENTS SESSION 6
9:20	Flash talks Moderated by Jordi Vila (Barcelona Institute for Global Health (ISGlobal), Barcelona) Jury: Domingo Gargallo-Viola (ABAC Therapeutics, Barcelona) Núria Martí (Biocat, Barcelona) Seamus O’Brien (GARDP, Geneva, Switzerland)
10:10	How to stimulate innovation in the public and private sectors? Joan Bigorra (Barcelona Institute for Global Health (ISGlobal), Barcelona)
10:30	Science and policy interface: JPI on AMR Laura Marin (JPI-AMR, Stockholm, Sweden)
11:00	Public-Private Partnership to address the public health challenge of antibiotic resistance Seamus O’Brien (GARDP, Geneva, Switzerland)
11:20	Coffe break and networking
11:50	Wellcome Trust Initiatives to tackle antimicrobial resistance Gemma Buckland-Merrett (Wellcome Trust, London, UK)
12:10	The role of Marie Skłodowska-Curie actions in the fight against Antimicrobial Resistance Gaetano Castaldo (European Commission-Research Executive Agency, Brussels, Belgium)
12:20	Discussion panel Moderated by Jordi Vila (Barcelona Institute for Global Health (ISGlobal), Barcelona) Joan Bigorra (Barcelona Institute for Global Health (ISGlobal), Barcelona) Laura Marin (JPI-AMR, Stockholm, Sweden) Seamus O’Brien (GARDP, Geneva, Switzerland) Gemma Buckland -Merrett (Wellcome Trust, London, UK) Gaetano Castaldo (European Commission-Research Executive Agency, Brussels, Belgium)
12:50	Closing remarks and farewell